Showing posts with label Anastrazole. Show all posts
Showing posts with label Anastrazole. Show all posts

Wednesday, February 22, 2012

Updates...



It's been a few weeks since I've posted so I'm going to keep it simple by bullet pointing what's been going on with us.  I said simple, not brief.

  • We did injections last month.  We were super excited about that because we were hoping to get more aggressive with our approach since we have a cutoff date in mind.  We went in for our scan and had ONE follicle.  I was really floored.  I'd been expecting 2-4 so that we would have a better chance at conceiving.  No such luck.  It's frustrating when you spend that much money and anxiety over something and it doesn't do what you hoped it would do.  Then again, that's the chance you take with this mess.  We went forward with the IUI because the doc said if money wasn't an issue, they'd recommend it because it does improve your chances even w/ one follie.  We decided to pretend money wasn't an issue. :)  Isn't money always an issue when you're going through fertility treatments?  It's friggin' expensive!  If you didn't have a tight budget before treatments, you do now.  Anyway, we found out a few weeks ago the IUI wasn't successful.
  • I had a long talk w/ my RE that day and asked her if we could go back to Clomid for one month because it was obvious to me that Anastrazole wasn't going to work and I wanted to wait another month before doing another round of injections. They want to double my dosage of Bravelle in hopes for more follicles so from a cost standpoint, we wanted to wait a month.  Dr. S thought Clomid was a good plan since I had consistently ended up with 2-3 follicles per cycle on Clomid.  The whole reason she put me on Anastrazole was to keep my lining from thinning out but I was still averaging between 9-12 mm (same as on Clomid) so I didn't really see any progression, we actually saw the opposite b/c we saw less follicles, same lining - go figure.  She doubled my Clomid dose and I started that on CD3.  She said we were going to start pushing the envelope.  I kind of wondered why we weren't pushing said envelope a little sooner than this, but I decided some things are better left unsaid.
  • On CD4 I developed a massive headache that ended up becoming a really wretched migraine that lasted for five days.  I was miserable, but it was worth it.  At my scan on Sunday, we got the good news that we had a total of four follicles.  11, 12, 16, 21 mm.  Lining was 7 mm, lower than usual.  What's crazy is that she said that was still "a-ok" and she was only concerned if it was 5 or below.  (Which made me wonder why she ever took me off Clomid in the first place!!?!?)  We triggered Monday morning, had our IUI yesterday morning and I came home and rested the WHOLE day just to encourage everything to stay where it needed to stay.  Oh, and Rik crossed the finish line strong with 30 million on IUI day so this month is looking good for all intents and purposes!  We'll see what happens.  Please pray for us as we only have two months left to conceive and then we're moving on.  That's not written in stone or anything, but....that's where we're at currently.
  • Time is just flying by these days.  Friends of ours that started trying to have children after we started this journey are now having baby #2 in a few months.  I'm really happy for them, it's just crazy how long we've been going through all of this (and I know it's nothing compared to some of the other stories we've heard!)...and we still aren't there yet.  I was thinking today that while I long to have a baby and want us to have a family of our own, it's not something that even seems like a possible reality to me anymore.  It just seems impossible that we will ever have a three part family, baby stuff laying around our living room, bottles in the cabinets, toys (not of the dog variety) all over the place or a nursery.  Those just do not seem like attainable dreams any more.  They are just dreams it seems and sometimes, that's difficult to get past.  It makes me think more and more we're wasting our time, even though I know we may NOT be.  Does this even make sense?  I'm not down, or sad or anything right now, it's just something that was on my mind today.  I just don't feel in my heart like we will EVER have a child.  The thought of it seems preposterous.  I could almost see us going to the moon on a hover craft before I could imagine us taking our own child to the playground for an afternoon.  But, I guess we'll see.  Hope leaves and then comes back in the same minute these days...which leads me to my next point...
  • We're going to an adoption education class next Tuesday.  I was really pumped about this but now I'm a little leery.  I don't know if it's because I'm so hopeful this month is "our month" (see, hope has re-entered the program) or if it's because of my feelings noted in the previous bullet point.  It just seems like even if we went down that path, something would still happen to where we never succeeded (aaaand hope exits stage right).  I'm downright scared of that being the case.  I don't know what we'll learn or what we'll decide but hopefully, it's informative and I come away from it with a sense of peace.  I'm just scared of getting hurt by that process too.  I think some of these feelings are also a bit of a defense mechanism I'm throwing up to protect my heart a little....maybe.
  • In other great news, a good friend of mine found out she's pregnant after trying to conceive for quite a while.  It's still early for them but I am so excited for her.  It's such a warm feeling to see someone who has gone through a lot of the same struggles we have gone through finally get the great news they've been hoping, waiting and praying for.  They are very special people and will make amazing parents.  I couldn't be happier for them!
  • Rik's the new head coach of a high school baseball team here in town.  They've been conditioning for months and finally got started with tryouts and practices in the past few weeks.  The team had their first scrimmage game this weekend and I have to admit, I was SO proud of my husband.  Seeing him out there in his uniform, talking to the kids, working so hard on the field, working with the parents, making a difference for some of these guys....it was just a great thing to see.  All of his hard work has paid off and I am so happy for him.  Baseball has been such a huge part of his life, it's heartwarming to see him stepping from the role of player to coach and thriving in that role.  The kids love him and the parents and faculty members can't say enough good things about his efforts so far.  Did I mention I'm proud of him?  :)
  • I went to watch my nephew, Matthew, play soccer last Friday night.  It's his first year of high school soccer and it's much more competitive and aggressive than the rec league or middle school soccer he is accustomed to.  He did great!  I sat in the stands, cheering against my old high school (weird!) and laughed myself silly over my niece and her crazy sense of humor.  Mallory's 11 years old and like Rik said last night, you never know what she's going to say or do next and it's adorably entertaining.  I honestly just LOVE being around her.  For about 20 minutes, she spoke with a British accent telling us stories about her classmates at school, then she was imitating how a girl on her softball team runs (imagine swinging your arms back and forth very quickly while you're flapping like a chicken) in front of everyone without the slightest bit of embarrassment.  She's hilarious!  My mom and stepdad came out too and we all had a great time.  Owen (nephew #2) wasn't as interested in hanging out with us since he had a friend with him but that's ok...I remember being 13 and being way too cool.  It was such a great night just being with my family and it still warms my heart to think about it.  I love them all so much. 
  • Mallory invited me to come to her "Parent Shadow" day at her school yesterday (isn't that precious?) and we had a great time.  I went to lunch with her and then joined her in her 4th period class.  I absolutely loved it!  I felt honored she would ask me to go and be her stand-in Mom.  She has an amazing step-mom but it feels great to know she still loves her Aunt Shae Shae now and then.  :)
Ok, enough for now.  If you're still hanging around, here's a picture or two as a pay-off.



Someone in Altoid's market department never battled infertily.


This is my Mallory.  Proof of her insane personality that is such a joy to be around!
Matthew, Me and Mallory being our normal selves while Dad drove us around town last month.

Owen resting his beautiful eyes while we finished up our shopping.  Did I mention my brother makes beautiful kids?

Maddox (adopted nephew) was my date two Friday's ago.  He had raspberry sherbert!  We had so much fun!


Mallory and Chloe at Parent Shadow Day yesterday!  You can see how "snaggly" Mallory is in this picture.  She usually won't smile because she hates having snaggle teef.

Sunday, January 8, 2012

I'm still here....taking up more space than usual.

Hey everyone.  Sorry I've been missing in action lately.  We had family in town, lots of Christmas dinners, then my birthday, then New Year's and honestly, it's taken me a week or so to fully recover.  My last post was full of anger, self-pity and sadness.  I'm feeling better today.  I have a better perspective and I'm doing what I can to keep the shadows at bay.  So far, so good.

While I was feeling sorry for myself, one of my favorite bloggers received some very sad and disappointing news over Christmas and it breaks my heart for her.  If you're the praying type, please send up a few prayers for her and her husband.  They need mercy and peace and at least some level of understanding bestowed upon them and even with these things in abundance, their hearts are going to take a long time to heal.

As far as my situation goes, we had another setback this past cycle.  The Anastrazole decided to hate me again and we produced only one follicle and Dr. S felt we should cancel the IUI we had planned and work with "timed intercourse" instead.  We were both pretty disappointed to say the least.  Then she went back to the ol' "next month we'll try injections" scenario (I feel like I'm riding on a gigantic yo-yo sometimes with this injection topic with her).  I just don't understand why we're not going back with Clomid which gave us the desired response on all levels.  I'm averaging the same thickness of my endometrium on Anastrazole as I did with Clomid so I don't get why we can't just stick with that since I was responding so well to it.  Oh well, I'm just the patient.  I'll do whatever will give us the best chance.

Which leads me to my next bit of information.  I think we're pretty close to being done.  Done with trying for a biological child.  Both of us go back and forth on the subject but I think that just indicates we're getting closer to giving up.  Sometimes, Rik is the one saying he's just tired of seeing us go through the emotional stuff.  Then it's me saying I'm tired of it.  We just both never seem to be tired of it at the same time.  :)  So for now, we've decided we're going to give it through April and then move on.  We may change our minds once April gets here and the panic sets in and reality hits us, but for now, that's where we are.  Realizing you will never have a biological child is going to be a hard pill to swallow.  Some of you have already taken that pill and are making it through each day somehow.  Some of you continued to battle through this infertility business and it paid off.

The doctor thinks we may have a fertilization issue which could only be corrected by IVF.  That's not something either of us want to do or try.  If I'm going to spend that kind of money, I want to bet on a sure thing.  Then again, I know adoption is never a sure thing...I'm learning that more and more the more people I meet and talk to about it.  I just can't imagine spending $20k on IVF and having it fail when I could spend a little more than that and have a better chance of bringing home a child that needs a family like ours just as much as we need it.  I won't love the child any less.  And when I think of all the children that would give anything to be loved and care for by a mom and a dad, it just seems wrong (for ME) to put my need for a biological child above that.  I don't think it's wrong for everyone, I just feel in my heart that it would be wrong for me.  It's very likely that by March or April I will feel very differently, but for now...that's where I'm sitting.  Who knows what will happen when we're actually facing that decision and have to make a choice to continue or make ourselves Plan B for a child whose Plan A fell through?

Sidenote of sorts....One of my former co-workers just picked up her daughter in China after waiting for SEVEN years for her.  In the meantime, she adopted one little boy domestically and managed to have a surprise pregnancy of her own as well.  It tugs on my heartstrings more than I can say to realize that even though she was born in their hearts as their first child, she was the last one to physically join their family.  Seven years.....wow.  She is a beautiful little girl and I'm sure they would do it all over again in a minute.

I am going to adoption retreat in Buford, Georgia at the end of this month with one of my blogger (and IRL) friends, Jennifer over at A Journey of Babysteps.  I'm excited, but very nervous because the retreat will be full of women already in the process of adopting and women who actually have already adopted. I am hoping that there are some women like me who know very little about the process but are interested in learning as much as they can about it.  Hopefully, it won't all be over my head.

Now, I'm going to spend a while going through all your blogs and checking up on each of you.  I'm sorry I've not been here for you these past few weeks.  I'm ashamed of myself for wallowing in this tarpit of emotions - I'll do better in the future and hopefully, none of you will have to check in on me to make sure I'm still alive.  :)  Love to you all.

Shannon

Wednesday, November 23, 2011

To Smite or Not To Smite?

Alright, let's get this update out of the way because I've been putting it off long enough.  Obviously, I shared with you gorgeous ladies (& Doc) that our last IUI failed.  For whatever reason, even though we were hesitant at first to go forward with the IUI after how little response we got out of the Anastrazole, I managed to get myself all worked up into a tizzy thinking that little scrapper follicle of ours was going to produce the most amazing and receptive egg EVER and turn out to be our miraculous and precious lab-love-child.  It wasn't to be.  For reasons that we mortals (as usual) will never understand.  I wish I was one of the enlightened ones from time to time but apparently that dumb-founded look suits me better in His eyes?

With me, I usually only have about three days to be really sad about a failed attempt.  I take a test or have my labs done and usually start that day, sometimes before the labs are even back.  Something about those tests MUST send out the signal and here comes the Goddess of Endometrium Linings in her gorgeous red chariot (sticking w/ the Gods theme?)...  Anyway, back to me being mortally dumb-founded and sad for three days.  I usually start some type of new treatment cycle on day three or day five depending on what we're trying and so the sadness is replaced by acceptance, which is replaced by focus, which is then trumped by determination which then blossoms into hope all over again.  Rollercoaster anyone?  Six Flags has nothing on IF.  Fo' real.

So anywho, I called the RE's office to tell them my test was negative since she had me test at home (which still bothers me because I don't feel "important" enough for them to test me in their office and don't they know I need to feel catered to/pampered?  I want them to stick me and make me bleed and tell me personally that this didn't work!  For those of you that know me, you know why that sounds completely insane - I'm a swooner of the worst kind when it comes to needles, or at least I was in my pre-IF life.) and the nurse called back to let me know they were there if I needed anything and to let them know if we decided to pursue another treatment cycle.  Naturally, I jumped right on board and told her we were definitely interested in the next cycle.  I told her what Dr. S had recommended at our previous IUI (in case it failed) which was possibly combining the Anastrazole with something else or doing Clomid and injectables.  She said she'd call me back after she spoke w/ Dr. S.

She called me back and gave me the kind of news that leaves you dumber-founded for a few days and asking a ton of questions that make you look like a know-it-all and a control-freak all at the same time.  She wanted us to try the Anastrazole again.  Nothing else.  The nurse kept saying how starting injectables takes some time, you have to pre-order the meds, take a class on them, go over payment options, etc. and she kept making me feel like I had been the one to recommend we do that next.  All I had done was tell her what Dr. S told us we might try next!  So of course, I back-pedal and try to explain that I wasn't PUSHING for injectables, she had just been wondering what Dr. S might want to do so I threw out what Dr. S had told us.  Don't you HATE that feeling when someone misunderstands you and the more you try to explain it, the more ridiculous you sound?  Sometimes, well-timed silence hath more eloquence than speech.  Ugh.

So, I asked her why we were only doing the Anastrazole after my body didn't respond well to it.  She said because it keeps your endometrium thick (triple stripe style) and makes a good environment for the fertilized egg to implant in.  I get that.  But on Clomid, my endometrium was always thick and my former RE always seemed happy that it looked so great.  AND I produced several follicles (which obviously weren't successful, but still).  I just don't understand why we are doing this again with nothing else.  It feels like a filler month while we move on to injectables.  I produce one follie a month on my own.  That's not a problem.  My endometrium is never super thin.  That's not a problem.  So why are we doing NOTHING more aggressive than taking these stupid pills that did nothing for me!?  And then, to beat it all, she said if THIS fails, we'll move on to injectables but only after we know this fails so that's another month of ordering meds and training and blah blah blah.  I wanted to take up the Goddess's tampon shaped trident and smite the nurse through the phone I was so upset!

So, what do you think?  I mean should I have pushed for something more aggressive?  This is our 35th month of TTC.  I'm tired of being so passive.  We aren't monitored much, the nurse told me to take an OPK and once positive to schedule my IUI for the next day and I had to ask her if we could have an ultrasound on day 10 or 11 to know how well the Anastrazole was working this month.  I just feel hung out to dry or something.  Am I being too sensitive here?

I've been a good patient though and I have taken my stupid friggin Anastrazole every day like a good girl and do my best not to get more depressed about the whole situation.  Sadness hasn't really turned into acceptance which will hinder focus and determination from making an appearance and probably erase hope completely this month.   So, I've decided this mortal stuff sucks.

Tuesday, November 1, 2011

One in the ovary is worth two in the...no, wait...um....

So, got my scan on yesterday at the doctor's office.  It showed me what I was already expecting.  No, not expecting like that, expecting as in I just knew it.  I've gotten so accustomed to seeing the ultrasound machine images of my girl parts that I knew exactly what she was (or wasn't) seeing.

See, in the past, when they've done our scan, we've gone through the measuring of the endometrium lining - which was just mediocre since Clomid tends to thin your lining out a little bit - and then onto the ovaries.  It's a routine all infertile couples go through and figure out and grow accustomed to seeing.  How many of you think you could do your own scan at this point?  Well, with a little help unless you're like Gumby.  Anyway, through the grainy black and white, you're able to distinguish your triple stripe, then the dark circles come into view and you can almost immediately tell what you're going to be dealing with for that cycle.  It's reassuring to see those little black blobs show up because you know that something is working properly for a change.  At least that is how I feel.  Usually.

On Clomid, my body responded well.  No hot flashes, no mood swings, nothing.  I've actually felt happier while on Clomid.  Odd huh?  Dr. S thought so.  Anyway, we've seen follies as big as 33 mm across.  We've seen them as small as about 11 mm.  We've never seen less than three follicles that were "mature" and once, I think we had about five that were good, mature, healthy possibilities.  I've always been pleased with that (other than the scary big #33).  So, there I sat (laid) yesterday, on CD11, looking at the screen, seeing my ultra thick, luscious lining (ok, so the Anastrazole did do that right) and just waiting to see if my body had liked the new medicine as much as the old medicine.  She went straight to the right ovary and the black and white grainy business never changed...just more black and white graininess.  She wiggled the DC around and finally, two little marbles appeared that were just tiny.  She didn't even measure them they were so small.   She said something about the right ovary not looking too promising and moved over to the left side.  After just a second, our one follicle popped up on the screen.  Nothing too dramatic, it measured about 16mm on CD11 so in another few days, who knows where it'll be.  We've had two follicles in the past grow about 6-8 mm overnight so we're hoping this little follie will grow a little more, but not too much.

Rik says he feels pretty good about this little guy.  He even tossed out the idea that maybe he is just such a tough and scrappy little follie that he ate the other follies and he's the last one standing.  King of the hill style.  I couldn't help but smile.  My husband knows just what to say sometimes.  Dr. S asked us to pee on a stick the next few evenings and once we come up with a positive OPK, we can either do another IUI and hope our one follicle is a good one (it only takes one) or she can give us our trigger shot and we can do the IUI then.

Here are my thoughts (as if this whole novella isn't already full of my thoughts), I don't know if we should drop the moolah on an IUI when we had such a poor showing of follicles (no offense to my one little scrapper) because technically, couldn't I do this much on my own?  How much will it tip the scale in our favor?  I have no problem ovulating.  It's getting the two key ingredients together to make an...um.....omelet maybe?  What takes two ingredients? ok, I can't think of a good food analogy here, but you get the point.  Something fantastic.

Maybe I've just answered my own question though....I love blogging.  The IUI would give those two key ingredients their best chance to get together and make something wonderful.  Since that seems to be the problem, maybe the IUI is the answer.  Especially if in the past, the endometriosis was making this process tougher and has now been eliminated.  I was just feeling like we should try on our own, call this month a loss and jump back in with both feet next month.  While we're dropping the money on this, I want to give us our best chance possible, ya know?

ergh...I don't know what to do.  Rik said he thinks if we don't do this cycle just because of the money factor, we'd regret it later and he's probably right.  It does just take one egg.  And it's not like the other months (with all their glory) have been successful.  I do find it ironic though that my left ovary is so active.  Always the bigger producer, also the one with the cyst and now 3 weeks after surgery on it, it's our only shot.  Show off.

So, what do you ladies (& Doc) think we should do?  I need some advice.  Also, Dr. S said that for next month, if we're unsuccessful this month, we'll either go back to Clomid and some type of injectable or do the Anastrazole in combination with something else.  I don't remember exactly what she said though because once she said "injectable" I pretty much heard nothing but horror film music the remainder of the visit.''   Ugh.  Solo pronto!  I guess....

In other news, Rik has already finished a new post for all you gals (& Doc) but I had to post this before I posted his so that I don't feel like such a slacker.  Also, all grammatical errors can be chalked up to the fact that THIS little lady won't stop pawing my arm and dropping her ball on my lap.  How can I resist this face?


Tess is a jealous creature.